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Based on experiments with this organoid model of small airway epithelia, and comparisons with 16HBE14o- and other cell types expressing normal CFTR, we predict that inflammation in the COVID-19 airway may be mediated by inhibition of CFTR signaling by the SARS-CoV-2 spike protein, thus inducing a cystic fibrosis-like clinical phenotype

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Also, measurement of 5-oxoproline levels in blood or urine is indicated to identify the interaction of these two drugs with certainty and to have insight into the severity of the accumulation

The supernatant was discarded, and the total RNA was dissolved in 30 L of DEPC-treated water

Sperm motility was categorized as motile and non-motile, and the percentage of motile sperm was obtained for each rat